Human FGFR4 activation kit by CRISPRa

SKU
GA101587
FGFR4 CRISPRa kit - CRISPR gene activation of human fibroblast growth factor receptor 4
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol FGFR4
Locus ID 2264
Components

GA101587G1, FGFR4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101587G2, FGFR4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101587G3, FGFR4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001291980, NM_002011, NM_022963, NM_213647, NM_001354984
UniProt ID P22455
Synonyms CD334; JTK2; TKF
Summary The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. provided by RefSeq, Aug 2017
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Resources
Other Versions
SKU Description Size Price
KN204230 FGFR4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN204230BN FGFR4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN204230LP FGFR4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204230RB FGFR4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404230 FGFR4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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