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Human ERCC1 activation kit by CRISPRa

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SKU
GA101444
ERCC1 CRISPRa kit - CRISPR gene activation of human ERCC excision repair 1, endonuclease non-catalytic subunit
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA500622 Anti-ERCC1 mouse monoclonal antibody, clone OTI1A3 (formerly 1A3) 100 ul
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RC200478 ERCC1 (Myc-DDK-tagged)-Human excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) (ERCC1), transcript variant 2
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Other products for "ERCC1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ERCC1
Locus ID 2067
Components

GA101444G1, ERCC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101444G2, ERCC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101444G3, ERCC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001166049, NM_001983, NM_202001, NM_001369409, NM_001369414, NM_001369416, NM_001369419, NM_001369408, NM_001369410, NM_001369411, NM_001369412, NM_001369413, NM_001369415, NM_001369417, NM_001369418
UniProt ID P07992
Synonyms COFS4; RAD10; UV20
Summary The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. provided by RefSeq, Oct 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN200478 ERCC1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200478BN ERCC1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200478LP ERCC1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200478RB ERCC1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400478 ERCC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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