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Human ESE1 (ELF3) activation kit by CRISPRa

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SKU
GA101385
ELF3 CRISPRa kit - CRISPR gene activation of human E74 like ETS transcription factor 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA809989 ELF3 mouse monoclonal antibody,clone OTI6G6 100 ul
$447.00
RC200631 ELF3 (Myc-DDK-tagged)-Human E74-like factor 3 (ets domain transcription factor, epithelial-specific ) (ELF3), transcript variant 1
10 ug
$457.00

Other products for "ELF3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ELF3
Locus ID 1999
Components

GA101385G1, ESE1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101385G2, ESE1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101385G3, ESE1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001114309, NM_004433
UniProt ID P78545
Synonyms EPR-1; ERT; ESE-1; ESX
Summary Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGAAT. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN400631 ELF3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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