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Human gp340 (DMBT1) activation kit by CRISPRa

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SKU
GA101219
DMBT1 CRISPRa kit - CRISPR gene activation of human deleted in malignant brain tumors 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA350650 Rabbit Polyclonal Anti-DMBT1 Antibody
100 ul
$205.00
RC215454 DMBT1 (Myc-DDK-tagged)-Human deleted in malignant brain tumors 1 (DMBT1), transcript variant 2
10 ug
$2,987.00

Other products for "DMBT1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DMBT1
Locus ID 1755
Components

GA101219G1, gp340 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101219G2, gp340 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101219G3, gp340 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001320644, NM_004406, NM_007329, NM_017579
UniProt ID Q9UGM3
Synonyms GP340; muclin; SAG; SALSA
Summary Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system. provided by RefSeq, Mar 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN415454 DMBT1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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