Human GADD45A activation kit by CRISPRa

SKU
GA101162
GADD45A CRISPRa kit - CRISPR gene activation of human growth arrest and DNA damage inducible alpha
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GADD45A
Locus ID 1647
Components

GA101162G1, GADD45A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101162G2, GADD45A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101162G3, GADD45A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001199741, NM_001199742, NM_001924
UniProt ID P24522
Synonyms DDIT1; GADD45
Summary This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.provided by RefSeq, Dec 2010
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Documents
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Other Versions
SKU Description Size Price
KN404005 GADD45A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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