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Human CYP27B1 activation kit by CRISPRa

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SKU
GA101122
CYP27B1 CRISPRa kit - CRISPR gene activation of human cytochrome P450 family 27 subfamily B member 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA325091 CYP27B1 Antibody (C-term)
200 ul
$645.00
RC222840 CYP27B1 (Myc-DDK-tagged)-Human cytochrome P450, family 27, subfamily B, polypeptide 1 (CYP27B1), nuclear gene encoding mitochondrial protein
10 ug
$473.00

Other products for "CYP27B1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CYP27B1
Locus ID 1594
Components

GA101122G1, CYP27B1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101122G2, CYP27B1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101122G3, CYP27B1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000785
UniProt ID O15528
Synonyms CP2B; CYP1; CYP1alpha; CYP27B; P450c1; PDDR; VDD1; VDDR; VDDRI; VDR
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN222840 CYP27B1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN222840BN CYP27B1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN222840LP CYP27B1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN222840RB CYP27B1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN422840 CYP27B1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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