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Human COX11 activation kit by CRISPRa

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SKU
GA100944
COX11 CRISPRa kit - CRISPR gene activation of human cytochrome c oxidase copper chaperone COX11
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA323960 Anti-COX11 Rabbit Polyclonal Antibody
100 ul
$305.00
RC203238 COX11 (Myc-DDK-tagged)-Human COX11 cytochrome c oxidase assembly homolog (yeast) (COX11), nuclear gene encoding mitochondrial protein, transcript variant 1
10 ug
$300.00

Other products for "COX11"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol COX11
Locus ID 1353
Components

GA100944G1, COX11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100944G2, COX11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100944G3, COX11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001162861, NM_001162862, NM_001321518, NM_004375, NR_027941, NR_027942, NR_135677
UniProt ID Q9Y6N1
Synonyms COX11P
Summary Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6. provided by RefSeq, Jun 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN203238 COX11 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203238BN COX11 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203238LP COX11 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN203238RB COX11 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN403238 COX11 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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