Human CHRM2 activation kit by CRISPRa

SKU
GA100806
CHRM2 CRISPRa kit - CRISPR gene activation of human cholinergic receptor muscarinic 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CHRM2
Locus ID 1129
Components

GA100806G1, CHRM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100806G2, CHRM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100806G3, CHRM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000739, NM_001006626, NM_001006627, NM_001006628, NM_001006629, NM_001006630, NM_001006631, NM_001006632, NM_001006633
UniProt ID P08172
Synonyms HM2
Summary The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
KN411436 CHRM2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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