OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Human p15 INK4b (CDKN2B) activation kit by CRISPRa

Be the first to review this product
SKU
GA100742
CDKN2B CRISPRa kit - CRISPR gene activation of human cyclin dependent kinase inhibitor 2B
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA505206 CDKN2B (p15 INK4b) mouse monoclonal antibody, clone OTI3B6 (formerly 3B6) 100 ul
$447.00
RC204895 CDKN2B (Myc-DDK-tagged)-Human cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) (CDKN2B), transcript variant 1
10 ug
$150.00

Other products for "CDKN2B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CDKN2B
Locus ID 1030
Components

GA100742G1, p15 INK4b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100742G2, p15 INK4b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100742G3, p15 INK4b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_004936, NM_078487
UniProt ID P42772
Synonyms CDK4I; INK4B; MTS2; P15; p15INK4b; TP15
Summary This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. provided by RefSeq, Jul 2008
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN204895 CDKN2B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204895BN CDKN2B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204895LP CDKN2B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN204895RB CDKN2B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN404895 CDKN2B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products