Human Caspase 9 (CASP9) activation kit by CRISPRa

SKU
GA100595
CASP9 CRISPRa kit - CRISPR gene activation of human caspase 9
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CASP9
Locus ID 842
Components

GA100595G1, Caspase 9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100595G2, Caspase 9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100595G3, Caspase 9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001229, NM_001278054, NM_032996, NR_102732, NR_102733
UniProt ID P55211
Synonyms APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56
Summary This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. provided by RefSeq, May 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN400635 CASP9 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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