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Human Caspase 3 (CASP3) activation kit by CRISPRa

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SKU
GA100589
CASP3 CRISPRa kit - CRISPR gene activation of human caspase 3
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC223662 CASP3 (Myc-DDK-tagged)-Human caspase 3, apoptosis-related cysteine peptidase (CASP3), transcript variant alpha
10 ug
$300.00

Other products for "CASP3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CASP3
Locus ID 836
Components

GA100589G1, Caspase 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100589G2, Caspase 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100589G3, Caspase 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_004346, NM_032991, NM_001354777, NM_001354778, NM_001354779, NM_001354780, NM_001354781, NM_001354782, NM_001354783, NM_001354784
UniProt ID P42574
Synonyms CPP32; CPP32B; SCA-1
Summary The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. provided by RefSeq, Aug 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN404444 CASP3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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