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Human CAD activation kit by CRISPRa

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SKU
GA100553
CAD CRISPRa kit - CRISPR gene activation of human carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA812683 CAD mouse monoclonal antibody,clone OTI10A3 100 ul
$447.00
RC209469 CAD (Myc-DDK-tagged)-Human carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD)
10 ug
$2,754.00

Other products for "CAD"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CAD
Locus ID 790
Components

GA100553G1, CAD gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100553G2, CAD gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100553G3, CAD gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001306079, NM_004341
UniProt ID P27708
Synonyms CAD trifunctional protein; carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase; multifunctional protein CAD
Summary The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Apr 2015
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Documents
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Other Versions
SKU Description Size Price
KN409469 CAD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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