CAD Mouse Monoclonal Antibody [Clone ID: OTI10A3]
Specifications
| Product Data | |
| Clone Name | OTI10A3 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:250~500 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1918-2225 of human CAD (NP_004332) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
| Database Link | |
| Background | The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Apr 2015 |
| Synonyms | CDG1Z; DEE50; EIEE50; GATD4 |
| Reference Data | |
| Protein Categories | Enzyme: Ligase, Intracellular Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome |
| Protein Pathways | Alanine, aspartate and glutamate metabolism, Metabolic pathways, Pyrimidine metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI10A3" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF812683 | Carrier-free (BSA/glycerol-free) CAD mouse monoclonal antibody,clone OTI10A3 | 100 ug |
$620.00
|
|
| TA812683AM | CAD mouse monoclonal antibody,clone OTI10A3, Biotinylated | 100 ul |
$509.00
|
|
| TA812683BM | CAD mouse monoclonal antibody,clone OTI10A3, HRP conjugated | 100 ul |
$509.00
|
|
| TA812683S | CAD mouse monoclonal antibody,clone OTI10A3 | 30 ul |
$200.00
|
|
Citations
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