Human CaV1.3 (CACNA1D) activation kit by CRISPRa

SKU
GA100541
CACNA1D CRISPRa kit - CRISPR gene activation of human calcium voltage-gated channel subunit alpha1 D
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CACNA1D
Locus ID 776
Components

GA100541G1, CaV1.3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100541G2, CaV1.3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100541G3, CaV1.3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000720, NM_001128839, NM_001128840
UniProt ID Q01668
Synonyms CACH3; CACN4; CACNL1A2; Cav1.3; CCHL1A2; PASNA; SANDD
Summary Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Dec 2012
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Documents
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Other Versions
SKU Description Size Price
KN422854 CACNA1D - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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