CaV1.3 (CACNA1D) Rabbit Polyclonal Antibody

SKU
TA351020
Rabbit Polyclonal Anti-CACNA1D Antibody
  $205.00
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Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 50-200
Positive control: Human brain
Predicted cell location: Cytoplasm
Reactivity Human, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human CACNA1D
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name calcium voltage-gated channel subunit alpha1 D
Database Link
Background Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene.
Synonyms CACH3; CACN4; CACNL1A2; Cav1.3; CCHL1A2; PASNA; SANDD
Reference Data
Protein Categories Endocrine and metabolic diseases, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Ion Channels: Calcium, Transmembrane
Protein Pathways Alzheimer's disease, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Calcium signaling pathway, Cardiac muscle contraction, Dilated cardiomyopathy, GnRH signaling pathway, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway, Type II diabetes mellitus, Vascular smooth muscle contraction
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