Human CD147 (BSG) activation kit by CRISPRa

SKU GA100475

BSG CRISPRa kit - CRISPR gene activation of human basigin (Ok blood group)

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: BSG
• Locus ID: 682
• Components:

  GA100475G1, CD147 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100475G2, CD147 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100475G3, CD147 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001322243, NM_001728, NM_198589, NM_198590, NM_198591
• UniProt ID: P35613
• Synonyms: 5F7; CD147; EMMPRIN; OK; TCSF
• Summary: The protein encoded by this gene, basigin, is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. Basigin is also a member of the immunoglobulin superfamily, ubiquitously expressed in various tissues. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2020]