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Human BCL2L2 activation kit by CRISPRa

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SKU
GA100413
BCL2L2 CRISPRa kit - CRISPR gene activation of human BCL2 like 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA302168 Bcl-w Antibody (BH3 Domain Specific)
400 ul
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RC211152 BCL2L2 (Myc-DDK-tagged)-Human BCL2-like 2 (BCL2L2), transcript variant 1
10 ug
$300.00

Other products for "BCL2L2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol BCL2L2
Locus ID 599
Components

GA100413G1, BCL2L2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100413G2, BCL2L2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100413G3, BCL2L2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001199839, NM_004050
UniProt ID Q92843
Synonyms BCL-W; BCL2-L-2; BCLW; PPP1R51
Summary This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. provided by RefSeq, Dec 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN411152 BCL2L2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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