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Human ATRX activation kit by CRISPRa

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SKU
GA100377
ATRX CRISPRa kit - CRISPR gene activation of human ATRX chromatin remodeler
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA592709 ATRX Rabbit monoclonal antibody,clone OTIR8G1
100 ul
$519.00
RC215176 ATRX (Myc-DDK-tagged)-Human alpha thalassemia/mental retardation syndrome X-linked (ATRX), transcript variant 1
10 ug
$3,084.00

Other products for "ATRX"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ATRX
Locus ID 546
Components

GA100377G1, ATRX gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100377G2, ATRX gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100377G3, ATRX gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000489, NM_138270, NM_138271
UniProt ID P46100
Synonyms ATR2; JMS; MRX52; MRXHF1; RAD54; RAD54L; SFM1; SHS; XH2; XNP; ZNF-HX
Summary The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with X-linked syndromes exhibiting cognitive disabilities as well as alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. provided by RefSeq, Jul 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN215176 ATRX - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215176BN ATRX - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215176LP ATRX - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN215176RB ATRX - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN415176 ATRX - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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