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Human ATP2B2 activation kit by CRISPRa

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SKU
GA100346
ATP2B2 CRISPRa kit - CRISPR gene activation of human ATPase plasma membrane Ca2+ transporting 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "ATP2B2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ATP2B2
Locus ID 491
Components

GA100346G1, ATP2B2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100346G2, ATP2B2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100346G3, ATP2B2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001001331, NM_001330611, NM_001683, NM_001353564, NM_001363862
UniProt ID Q01814
Synonyms PMCA2; PMCA2a; PMCA2i
Summary The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN421710 ATP2B2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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