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Human XIAP activation kit by CRISPRa

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SKU
GA100232
XIAP CRISPRa kit - CRISPR gene activation of human X-linked inhibitor of apoptosis
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA306170 Rabbit Polyclonal XIAP Antibody
100 ug
$640.00
RC207627 XIAP (Myc-DDK-tagged)-Human X-linked inhibitor of apoptosis (XIAP), transcript variant 1
10 ug
$457.00

Other products for "XIAP"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol XIAP
Locus ID 331
Components

GA100232G1, XIAP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100232G2, XIAP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100232G3, XIAP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001167, NM_001204401, NR_037916
UniProt ID P98170
Synonyms API3; BIRC4; hIAP-3; hIAP3; IAP-3; ILP1; MIHA; XLP2
Summary This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.provided by RefSeq, Feb 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN207627 XIAP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207627BN XIAP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207627LP XIAP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207627RB XIAP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN407627 XIAP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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