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Human APC activation kit by CRISPRa

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SKU
GA100225
APC CRISPRa kit - CRISPR gene activation of human APC regulator of WNT signaling pathway
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "APC"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol APC
Locus ID 324
Components

GA100225G1, APC gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100225G2, APC gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100225G3, APC gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000038, NM_001127510, NM_001127511, NM_001354895, NM_001354896, NM_001354897, NM_001354898, NM_001354899, NM_001354900, NM_001354901, NM_001354902, NM_001354903, NM_001354904, NM_001354905, NM_001354906
UniProt ID P25054
Synonyms BTPS2; DP2; DP2.5; DP3; GS; PPP1R46
Summary This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Mutations in the APC gene have been found to occur in most colorectal cancers. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. provided by RefSeq, Dec 2019
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Documents
Resources
Other Versions
SKU Description Size Price
KN211629 APC - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211629BN APC - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211629LP APC - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211629RB APC - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN411629 APC - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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