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APC Mouse Monoclonal Antibody [Clone ID: OTI2B8]

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SKU
TA803655
APC mouse monoclonal antibody, clone OTI2B8 (formerly 2B8)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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View other "APC or NM_001127511" antibodies

Specifications
Specifications
Product Data
Clone Name OTI2B8
Application IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 955-1382 of human APC (NP_001120983) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 311.5 kDa
Gene Name adenomatous polyposis coli
Database Link
Background This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. provided by RefSeq, Jul 2008
Synonyms BTPS2; DP2; DP2.5; DP3; GS; PPP1R46
Reference Data
Protein Categories Cancer: Brain and CNS, Cancer: Gastrointestinal, Cytokines, Endocrine and metabolic diseases, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Basal cell carcinoma, Colorectal cancer, Endometrial cancer, Pathways in cancer, Regulation of actin cytoskeleton, Wnt signaling pathway
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Other "OTI2B8" antibodies (4)
SKU Description Size Price
CF803655 Carrier-free (BSA/glycerol-free) APC mouse monoclonal antibody, clone OTI2B8 (formerly 2B8) 100 ug
$620.00
TA803655AM APC mouse monoclonal antibody, clone OTI2B8 (formerly 2B8), Biotinylated 100 ul
$509.00
TA803655BM APC mouse monoclonal antibody, clone OTI2B8 (formerly 2B8), HRP conjugated 100 ul
$509.00
TA803655S APC mouse monoclonal antibody, clone OTI2B8 (formerly 2B8) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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