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CD8A (NM_001145873) Human Recombinant Protein

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SKU
TP761250
Purified recombinant protein of Human CD8a molecule (CD8A), transcript variant 3, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Size:
50 ug
  $270.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length CD8A
Tag N-His
Predicted MW 23.5 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001139345
Locus ID 925
UniProt ID P01732
Cytogenetics 2p11.2
RefSeq Size 3177
RefSeq ORF 705
Synonyms CD8; Leu2; p32
Summary The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. provided by RefSeq, May 2020
Protein Categories ADC Targets, CD Markers, Immune system diseases, Intracellular Proteins, Membrane Proteins
Protein Families Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
Protein Pathways Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway
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Other "CD8A" proteins (13)
SKU Description Size Price
LC403530 Lyophilized CD8A HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC419749 Lyophilized CD8A HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC429040 Lyophilized CD8A HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY403530 Transient overexpression lysate of CD8a molecule (CD8A), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY419749 Transient overexpression lysate of CD8a molecule (CD8A), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY429040 Transient overexpression lysate of CD8a molecule (CD8A), transcript variant 3 (as WB positive control) 100 ug
$436.00
TP721308 Human CD8α Protein (C-His) 25 ug
$300.00
TP721309 Human CD8α Protein (C-His-Avi) 25 ug
$300.00
TP721310 Biotinylated Human CD8α Protein (C-His-Avi) 25 ug
$430.00
TP721311 PE Conjugated Human CD8α Protein (C-His) 25 ug
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TP721312 APC Conjugated Human CD8α Protein (C-His) 25 ug
$430.00
TP760215 Recombinant protein of human CD8a molecule (CD8A), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug 50 ug
$270.00
TP761244 Purified recombinant protein of Human CD8a molecule (CD8A), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug 50 ug
$270.00

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