CD70 Human Recombinant Protein

SKU
TP724019
Recombinant human CD70 protein with C-terminal human Fc and 6×His tag
  $905.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
CD70(Gln39-Pro193) hFc(Glu99-Ala330) 6×His
Tag C-Human Fc and 6×His Tag
Predicted MW The protein has a predicted molecular mass of 44.1 kDa after removal of the signal peptide.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
Reconstitution Method 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube.
2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000
3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL)
4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample.
Preparation Affinity purification
Storage Store the lyophilized protein at -20°C.
After reconstitution, store the protein at -80°C for 12 months.
Avoid repeated freezing and thawing.
Stability 12 months from date of despatch
Shipping Ambient
Reference Data
Locus ID 970
UniProt ID P32970
Synonyms CD70;CD27LG;TNFSF7;TNFSF7G;CD27L
Summary The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Protein Categories ADC Targets, CAR-T Targets, CD Markers, Cytokines, Immune system diseases, Intracellular Proteins, Membrane Proteins
Protein Families ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction
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Other "CD70" proteins (6)
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PH300410 CD70 MS Standard C13 and N15-labeled recombinant protein (NP_001243) 10 ug
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LY400501 Transient overexpression lysate of CD70 molecule (CD70) (as WB positive control) 100 ug
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TP700287 Purified recombinant protein of human CD70 molecule (CD70), with C-terminal Fc tag, expressed in human cells, 20 µg 20 ug
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TP723962 Recombinant human CD70 protein with N-terminal mouse Fc and C-terminal 6×His tag 100 ug
$905.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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