CD70 Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Human Fc and 6×His Tag |
| Predicted MW | The protein has a predicted molecular mass of 44.1 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
| Reconstitution Method | 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube. 2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000 3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL) 4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample. |
| Preparation | Affinity purification |
| Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
| Stability | 12 months from date of despatch |
| Shipping | Ambient |
| Reference Data | |
| Locus ID | 970 |
| UniProt ID | P32970 |
| Synonyms | CD70;CD27LG;TNFSF7;TNFSF7G;CD27L |
| Summary | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. |
| Protein Categories | ADC Targets, CAR-T Targets, CD Markers, Cytokines, Immune system diseases, Intracellular Proteins, Membrane Proteins |
| Protein Families | ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "CD70" proteins (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH300410 | CD70 MS Standard C13 and N15-labeled recombinant protein (NP_001243) | 10 ug |
$3,360.00
|
|
| LC400501 | Lyophilized CD70 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400501 | Transient overexpression lysate of CD70 molecule (CD70) (as WB positive control) | 100 ug |
$436.00
|
|
| TP300410 | Recombinant protein of human CD70 molecule (CD70), 20 µg | 20 ug |
$867.00
|
|
| TP700287 | Purified recombinant protein of human CD70 molecule (CD70), with C-terminal Fc tag, expressed in human cells, 20 µg | 20 ug |
$900.00
|
|
| TP723962 | Recombinant human CD70 protein with N-terminal mouse Fc and C-terminal 6×His tag | 100 ug |
$905.00
|
|
Citations
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