CD70 (NM_001252) Human Recombinant Protein
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 20.9 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | In vitro binding assay (PMID: 25730144) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001243 |
| Locus ID | 970 |
| UniProt ID | P32970 |
| Cytogenetics | 19p13.3 |
| RefSeq Size | 913 |
| RefSeq ORF | 579 |
| Synonyms | CD27-L; CD27L; CD27LG; LPFS3; TNFSF7; TNLG8A |
| Summary | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. provided by RefSeq, Jul 2008 |
| Protein Categories | ADC Targets, CAR-T Targets, CD Markers, Cytokines, Immune system diseases, Intracellular Proteins, Membrane Proteins |
| Protein Families | ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
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|---|---|---|---|---|
| PH300410 | CD70 MS Standard C13 and N15-labeled recombinant protein (NP_001243) | 10 ug |
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|
|
| LC400501 | Lyophilized CD70 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
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|
| LY400501 | Transient overexpression lysate of CD70 molecule (CD70) (as WB positive control) | 100 ug |
$436.00
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| TP700287 | Purified recombinant protein of human CD70 molecule (CD70), with C-terminal Fc tag, expressed in human cells, 20 µg | 20 ug |
$900.00
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|
| TP723962 | Recombinant human CD70 protein with N-terminal mouse Fc and C-terminal 6×His tag | 100 ug |
$905.00
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|
| TP724019 | Recombinant human CD70 protein with C-terminal human Fc and 6×His tag | 100 ug |
$905.00
|
|
Citations
Insights into the molecular basis of a bispecific antibody's target selectivity
Mazor, Hansen, Yang et al
MAbs (2015)
Mazor, Hansen, Yang et al
MAbs (2015)
Cited by 84
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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