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PAK4 (NM_005884) Human Recombinant Protein

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SKU
TP723906
Purified recombinant kinase domain protein of human p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 1, 100 µg
Size:
100 ug
  $2,845.00
5 Days*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
GPHMSHEQFR AALQLVVDPG DPRSYLDNFI KIGEGSTGIV CIATVRSSGK LVAVKKMDLR KQQRRELLFN EVVIMRDYQH ENVVEMYNSY LVGDELWVVM EFLEGGALTD IVTHTRMNEE QIAAVCLAVL QALSVLHAQG VIHRDIKSDS ILLTHDGRVK LSDFGFCAQV SKEVPRRKSL VGTPYWMAPE LISRLPYGPE VDIWSLGIMV IEMVDGEPPY FNEPPLKAMK MIRDNLPPRL KNLHKVSPSL KGFLDRLLVR DPAQRATAAE LLKHPFLAKA GPPASIVPLM RQNRT
Tag Tag Free
Predicted MW 33.3 kDa
Concentration lot specific
Purity >90% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10% glycerol, 5 mM DTT.
Bioactivity Specific activity was determined as 5,595 pmoles/min/µg, according to the Zlyte assay protocol
Endotoxin < 0.1 ng/µg of protein (< 1EU/µg)
Storage Store at -80°C.
Stability Stable at -80°C for 12 months from date of receipt. Protein should be thawed on ice. Protein can be flash-frozen in liquid nitrogen and stored at -80°C.
Shipping Dry Ice
Reference Data
RefSeq NP_005875
Locus ID 10298
UniProt ID O96013
Cytogenetics 19q13.2
RefSeq Size 2838
RefSeq ORF 1773
Summary PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Jul 2008
Protein Categories Enzyme: Kinases, Intracellular Proteins
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Axon guidance, ErbB signaling pathway, Focal adhesion, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway
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Other "PAK4" proteins (15)
SKU Description Size Price
PH302302 PAK4 MS Standard C13 and N15-labeled recombinant protein (NP_005875) 10 ug
$3,360.00
PH306847 PAK4 MS Standard C13 and N15-labeled recombinant protein (NP_001014831) 10 ug
$3,360.00
PH317097 PAK4 MS Standard C13 and N15-labeled recombinant protein (NP_001014832) 10 ug
$3,360.00
LC417002 Lyophilized PAK4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC423086 Lyophilized PAK4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC423087 Lyophilized PAK4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC423088 Lyophilized PAK4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY417002 Transient overexpression lysate of p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY423086 Transient overexpression lysate of p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY423087 Transient overexpression lysate of p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 3 (as WB positive control) 100 ug
$436.00
LY423088 Transient overexpression lysate of p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 5 (as WB positive control) 100 ug
$665.00
TP302302 Recombinant protein of human p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 1, 20 µg 20 ug
$867.00
TP306847 Recombinant protein of human p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 2, 20 µg 20 ug
$867.00
TP317097 Recombinant protein of human p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 3, 20 µg 20 ug
$867.00
TP723905 Purified recombinant kinase domain protein of human p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 1, 10 µg 10 ug
$820.00

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