EPCAM (NM_002354) Human Recombinant Protein

CAT#: TP720296

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Recombinant protein of human epithelial cell adhesion molecule (EPCAM)


Product Datasheet for 'TP720296'


  View other "EPCAM" proteins (5)

USD 300.00


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Size
    • 10 ug


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Specifications

Product Data
Description Recombinant protein of human epithelial cell adhesion molecule (EPCAM)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC201989, encoding the polypeptide (Gln24-Lys265) of human EPCAM
Tag C-His
Predicted MW 28.4 kDa
Concentration Resuspend the protein to the desired concentration in proper buffer.
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.2.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Storage Store at -80°C.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_002345
Locus ID 4072
Refseq Size 1528
Cytogenetics 2p21
Refseq ORF 942
Synonyms DIAR5; EGP-2; EGP40; EGP314; ESA; HNPCC8; KS1/4; KSA; M4S1; MIC18; MK-1; TACSTD1; TROP1
Summary This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
Protein Families ES Cell Differentiation/IPS, Transmembrane

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