HTRA1 (NM_002775) Human Recombinant Protein

CAT#: TP700208

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Recombinant protein of human HtrA serine peptidase 1 (HTRA1), S328A mutant, 20 ug


Product Datasheet for 'TP700208'


 Cited in 2 publications.

  View other "HTRA1" proteins (4)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human HtrA serine peptidase 1 (HTRA1), S328A mutant, 20 ug
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC222362 with a T982G mutation, encoding the mutant form (S328A) of human HTRA
Tag C-Myc/DDK
Predicted MW 49 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Bioactivity Protein degradation enzyme (PMID: 29269042)
Enzyme activity (PMID: 29572155)
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_002766
Locus ID 5654
Refseq Size 2133
Cytogenetics 10q26.13
Refseq ORF 443
Synonyms ARMD7; CADASIL2; CARASIL; HtrA; L56; ORF480; PRSS11
Summary This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Protease, Secreted Protein

Citations (2)

Documents

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