LCK (NM_005356) Human Recombinant Protein

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SKU
TP319375
Recombinant protein of human lymphocyte-specific protein tyrosine kinase (LCK), transcript variant 2, 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
Recombinant protein was produced with TrueORF clone, RC219375. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 57.8 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_005347
Locus ID 3932
UniProt ID P06239
Cytogenetics 1p35.2
RefSeq Size 2032
RefSeq ORF 1527
Synonyms IMD22; LSK; p56lck; pp58lck; YT16
Summary This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. provided by RefSeq, Aug 2016
Protein Categories Enzyme: Kinases, Immune system diseases, Intracellular Proteins
Protein Families Druggable Genome, Protein Kinase, Stem cell - Pluripotency
Protein Pathways Natural killer cell mediated cytotoxicity, Primary immunodeficiency, T cell receptor signaling pathway
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Other "LCK" proteins (5)
SKU Description Size Price
PH319375 LCK MS Standard C13 and N15-labeled recombinant protein (NP_005347) 10 ug
$3,360.00
LC401649 Lyophilized LCK HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC420808 Lyophilized LCK HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401649 Transient overexpression lysate of lymphocyte-specific protein tyrosine kinase (LCK), transcript variant 2 (as WB positive control) 100 ug
$665.00
LY420808 Transient overexpression lysate of lymphocyte-specific protein tyrosine kinase (LCK), transcript variant 1 (as WB positive control) 100 ug
$665.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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