DAB2IP (NM_032552) Human Recombinant Protein
SKU
TP314413
Purified recombinant protein of Homo sapiens DAB2 interacting protein (DAB2IP), transcript variant 1, 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 124.9 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_115941 |
| Locus ID | 153090 |
| UniProt ID | Q5VWQ8 |
| Cytogenetics | 9q33.2 |
| RefSeq Size | 5472 |
| RefSeq ORF | 3396 |
| Synonyms | AF9Q34; AIP-1; AIP1; DIP1/2 |
| Summary | DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005 PubMed 15386433).supplied by OMIM, May 2010 |
| Protein Categories | Growth Factors, Intracellular Proteins |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "DAB2IP" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH314413 | DAB2IP MS Standard C13 and N15-labeled recombinant protein (NP_115941) | 10 ug |
$3,360.00
|
|
| LC410041 | Lyophilized DAB2IP HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY410041 | Transient overexpression lysate of DAB2 interacting protein (DAB2IP), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
Citations
The RASSF1A Tumor Suppressor Binds the RasGAP DAB2IP and Modulates RAS Activation in Lung Cancer
Harrell Stewart, Schmidt, Donninger et al
Cancers (Basel) (2020) 12 (12) DOI: 10.3390/cancers12123807
Harrell Stewart, Schmidt, Donninger et al
Cancers (Basel) (2020) 12 (12) DOI: 10.3390/cancers12123807
Cited by 8
AI Summary: OriGene contributed to this study by providing a specific shRNA used to knock down RASSF1A expression in NCI-H1437 lung cancer cells, enabling the authors to investigate the role of RASSF1A in regulating RAS activation.
Snippet: … Knockdown of RASSF1A in NCI-H1792 cells was achieved using an shRNA described in [16], whereas the NCI-H1437 cells express a different shRNA purchased from Origene (described in [40]). … Knockdown of RASSF1A in NCI-H1792 cells was achieved using an shRNA described in [16], whereas the NCI-H1437 cells express a different shRNA purchased from Origene (described in [40]). …
Showing 1-1 of 1 papers.
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