PPAR gamma (PPARG) (NM_005037) Human Recombinant Protein

CAT#: TP312449

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Recombinant protein of human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 4


 Product Datasheet for 'TP312449'

  View other "PPARG" proteins (19)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 4
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 54.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_005028
Locus ID 5468
Refseq Size 1818
Cytogenetics 3p25.2
Refseq ORF 1431
Synonyms CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma
Summary This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways Huntington's disease, Pathways in cancer, PPAR signaling pathway, Thyroid cancer

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