KCNIP4 (NM_001035004) Human Recombinant Protein

CAT#: TP307464

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Recombinant protein of human Kv channel interacting protein 4 (KCNIP4), transcript variant 6


Product Datasheet for 'TP307464'


  View other "KCNIP4" proteins (19)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human Kv channel interacting protein 4 (KCNIP4), transcript variant 6
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC207464. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 21.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_001030176
Locus ID 80333
Refseq Size 2345
Cytogenetics 4p15.31-p15.2
Refseq ORF 753
Synonyms CALP; KCHIP4
Summary This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Ion Channels: Other

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