NCF1 (NM_000265) Human Recombinant Protein

CAT#: TP301233

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Recombinant protein of human neutrophil cytosolic factor 1 (NCF1)


 Product Datasheet for 'TP301233'

 Cited in 1 publication.

  View other "NCF1" proteins (6)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human neutrophil cytosolic factor 1 (NCF1)
Species Human
Expression Host HEK293T
Expression cDNA Clone or AA Sequence Recombinant protein was produced with TrueORF clone, RC201233. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag C-Myc/DDK
Predicted MW 44.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Bioactivity Enzyme substrate (PMID: 29195919)
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_000256
Locus ID 653361
Refseq Size 1409
Cytogenetics 7q11.23
Refseq ORF 1170
Synonyms NCF1A; NOXO2; p47phox; SH3PXD1A
Summary The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq, Jul 2008]
Protein Pathways Chemokine signaling pathway, Fc gamma R-mediated phagocytosis, Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton

Citations (1)

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