NCF1 (NM_000265) Human Recombinant Protein
$867.00
4 Weeks*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 44.5 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | Enzyme substrate (PMID: 29195919) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000256 |
| Locus ID | 653361 |
| UniProt ID | P14598 |
| Cytogenetics | 7q11.23 |
| RefSeq Size | 1409 |
| RefSeq ORF | 1170 |
| Synonyms | CGD1; NCF1A; NOXO2; p47phox; SH3PXD1A |
| Summary | The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. provided by RefSeq, Jul 2008 |
| Protein Categories | Growth Factors, Immune system diseases, Intracellular Proteins |
| Protein Pathways | Chemokine signaling pathway, Fc gamma R-mediated phagocytosis, Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "NCF1" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH301233 | NCF1 MS Standard C13 and N15-labeled recombinant protein (NP_000256) | 10 ug |
$3,360.00
|
|
| LC400103 | Lyophilized NCF1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400103 | Transient overexpression lysate of neutrophil cytosolic factor 1 (NCF1) (as WB positive control) | 100 ug |
$436.00
|
|
| TP761217 | Purified recombinant protein of Human neutrophil cytosolic factor 1 (NCF1), full length, with N-terminal HIS tag, expressed in E. coli, 50ug | 50 ug |
$270.00
|
|
Citations
S-Glutathionylation of p47phox sustains superoxide generation in activated neutrophils
Nagarkoti, Dubey, Awasthi et al
Biochim. Biophys. Acta (2018) 1865 (2), 444-454 DOI: 10.1016/j.bbamcr.2017.11.014
Nagarkoti, Dubey, Awasthi et al
Biochim. Biophys. Acta (2018) 1865 (2), 444-454 DOI: 10.1016/j.bbamcr.2017.11.014
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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