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STING (TMEM173) (NM_198282) Human Recombinant Protein

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SKU
LP308418
Lyophilized purified recombinant protein of Human transmembrane protein 173 (TMEM173), nuclear gene encoding mitochondrial protein, 20ug
Size:
20 ug
Formulation:
Lyophilized Liquid
  $867.00
2 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from TrueORF clone, RC208418, encoding the full-length of TMEM173
Tag C-terminal Myc-DDK tag
Predicted MW 42.2 kDa
Purity > 90% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.3
Reconstitution Method It is not recommended to reconstitute to a concentration less than 200 μg/mL in ddH2O.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Stability Stored at -20 to -70 ℃ for 1 year and avoid repeated freeze-thaw cycles after receipt; After reconstitution, the protein can be stored longer at -20 to -70 ℃, with aliquoting for single use recommended to prevent repeated freeze-thaw.
Shipping Blue Ice
Reference Data
RefSeq NP_938023
Locus ID 340061
UniProt ID Q86WV6
Cytogenetics 5q31.2
RefSeq Size 2223
RefSeq ORF 1137
Synonyms ERIS; hMITA; hSTING; MITA; MPYS; NET23; SAVI; STING; STING-beta; TMEM173
Summary This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. provided by RefSeq, Sep 2014
Protein Categories ADC Targets, Immune system diseases, Intracellular Proteins, Membrane Proteins
Protein Pathways Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway
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Other "STING" proteins (3)
SKU Description Size Price
PH308418 TMEM173 MS Standard C13 and N15-labeled recombinant protein (NP_938023) 10 ug
$3,360.00
LC405006 Lyophilized TMEM173 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY405006 Transient overexpression lysate of transmembrane protein 173 (TMEM173), nuclear gene encoding mitochondrial protein (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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