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STING (TMEM173) (NM_198282) Human Mass Spec Standard

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SKU
PH308418
TMEM173 MS Standard C13 and N15-labeled recombinant protein (NP_938023)
Size:
10 ug
  $3,360.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA505023 TMEM173 mouse monoclonal antibody, clone OTI4H1 (formerly 4H1) 100 ul
$447.00
LY405006 Transient overexpression lysate of transmembrane protein 173 (TMEM173), nuclear gene encoding mitochondrial protein (as WB positive control) 100 ug
$436.00

Other products for "STING or NM_198282"

Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC208418
Predicted MW 42.2 kDa
Protein Sequence
Protein Sequence
>RC208418 protein sequence
Red=Cloning site Green=Tags(s)

MPHSSLHPSIPCPRGHGAQKAALVLLSACLVTLWGLGEPPEHTLRYLVLHLASLQLGLLLNGVCSLAEEL
RHIHSRYRGSYWRTVRACLGCPLRRGALLLLSIYFYYSLPNAVGPPFTWMLALLGLSQALNILLGLKGLA
PAEISAVCEKGNFNVAHGLAWSYYIGYLRLILPELQARIRTYNQHYNNLLRGAVSQRLYILLPLDCGVPD
NLSMADPNIRFLDKLPQQTGDHAGIKDRVYSNSIYELLENGQRAGTCVLEYATPLQTLFAMSQYSQAGFS
REDRLEQAKLFCRTLEDILADAPESQNNCRLIAYQEPADDSSFSLSQEVLRHLRQEEKEEVTVGSLKTSA
VPSTSTMSQEPELLISGMEKPLPLRTDFS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_938023
RefSeq Size 2223
RefSeq ORF 1137
Synonyms ERIS; hMITA; hSTING; MITA; MPYS; NET23; SAVI; STING; STING-beta; TMEM173
Locus ID 340061
UniProt ID Q86WV6
Cytogenetics 5q31.2
Summary This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. provided by RefSeq, Sep 2014
Protein Pathways Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway
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Other "STING" proteins (3)
SKU Description Size Price
LC405006 Lyophilized TMEM173 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY405006 Transient overexpression lysate of transmembrane protein 173 (TMEM173), nuclear gene encoding mitochondrial protein (as WB positive control) 100 ug
$436.00
TP308418 Recombinant protein of human transmembrane protein 173 (TMEM173), 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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