PCBP2 (NM_001128914) Human Mass Spec Standard

SKU
PH325457
PCBP2 MS Standard C13 and N15-labeled recombinant protein (NP_001122386)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC225457
Predicted MW 33.3 kDa
Protein Sequence
Protein Sequence
>RC225457 representing NM_001128914
Red=Cloning site Green=Tags(s)

MDTGVIEGGLNVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFK
AFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPN
STERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTK
LHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPV
EGSTDRQVTITGSAASISLAQYLINVRLSSETGGMGSS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001122386
RefSeq ORF 954
Synonyms hnRNP-E2; HNRNPE2; HNRPE2
Locus ID 5094
UniProt ID Q15366
Cytogenetics 12q13.13
Summary The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. This gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jan 2018
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Other "PCBP2" proteins (21)
SKU Description Size Price
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LC403134 Lyophilized PCBP2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC417574 Lyophilized PCBP2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC420644 Lyophilized PCBP2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC427015 Lyophilized PCBP2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC427016 Lyophilized PCBP2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LC429233 Lyophilized PCBP2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LY403134 Transient overexpression lysate of poly(rC) binding protein 2 (PCBP2), transcript variant 2 (as WB positive control) 100 ug
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LY417574 Transient overexpression lysate of poly(rC) binding protein 2 (PCBP2), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY420644 Transient overexpression lysate of poly(rC) binding protein 2 (PCBP2), transcript variant 3 (as WB positive control) 100 ug
$436.00
LY427015 Transient overexpression lysate of poly(rC) binding protein 2 (PCBP2), transcript variant 6 (as WB positive control) 100 ug
$436.00
LY427016 Transient overexpression lysate of poly(rC) binding protein 2 (PCBP2), transcript variant 7 (as WB positive control) 100 ug
$436.00
LY429233 Transient overexpression lysate of poly(rC) binding protein 2 (PCBP2), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP300339 Recombinant protein of human poly(rC) binding protein 2 (PCBP2), transcript variant 2, 20 µg 20 ug
$737.00
TP310035 Recombinant protein of human poly(rC) binding protein 2 (PCBP2), transcript variant 1, 20 µg 20 ug
$737.00
TP313289 Purified recombinant protein of Homo sapiens poly(rC) binding protein 2 (PCBP2), transcript variant 3, 20 µg 20 ug
$737.00
TP325457 Purified recombinant protein of Homo sapiens poly(rC) binding protein 2 (PCBP2), transcript variant 7, 20 µg 20 ug
$737.00
TP325491 Purified recombinant protein of Homo sapiens poly(rC) binding protein 2 (PCBP2), transcript variant 6, 20 µg 20 ug
$737.00

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