PCBP2 (NM_001128914) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC225457 |
| Predicted MW | 33.3 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001122386 |
| RefSeq ORF | 954 |
| Synonyms | hnRNP-E2; HNRNPE2; HNRPE2 |
| Locus ID | 5094 |
| UniProt ID | Q15366 |
| Cytogenetics | 12q13.13 |
| Summary | The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. This gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jan 2018 |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PCBP2" proteins (21)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH300339 | PCBP2 MS Standard C13 and N15-labeled recombinant protein (NP_114366) | 10 ug |
$3,360.00
|
|
| PH310035 | PCBP2 MS Standard C13 and N15-labeled recombinant protein (NP_005007) | 10 ug |
$3,360.00
|
|
| PH313289 | PCBP2 MS Standard C13 and N15-labeled recombinant protein (NP_001092090) | 10 ug |
$3,360.00
|
|
| PH325491 | PCBP2 MS Standard C13 and N15-labeled recombinant protein (NP_001122385) | 10 ug |
$3,360.00
|
|
| LC403134 | Lyophilized PCBP2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC417574 | Lyophilized PCBP2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC420644 | Lyophilized PCBP2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC427015 | Lyophilized PCBP2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC427016 | Lyophilized PCBP2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC429233 | Lyophilized PCBP2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY403134 | Transient overexpression lysate of poly(rC) binding protein 2 (PCBP2), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY417574 | Transient overexpression lysate of poly(rC) binding protein 2 (PCBP2), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY420644 | Transient overexpression lysate of poly(rC) binding protein 2 (PCBP2), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| LY427015 | Transient overexpression lysate of poly(rC) binding protein 2 (PCBP2), transcript variant 6 (as WB positive control) | 100 ug |
$436.00
|
|
| LY427016 | Transient overexpression lysate of poly(rC) binding protein 2 (PCBP2), transcript variant 7 (as WB positive control) | 100 ug |
$436.00
|
|
| LY429233 | Transient overexpression lysate of poly(rC) binding protein 2 (PCBP2), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP300339 | Recombinant protein of human poly(rC) binding protein 2 (PCBP2), transcript variant 2, 20 µg | 20 ug |
$737.00
|
|
| TP310035 | Recombinant protein of human poly(rC) binding protein 2 (PCBP2), transcript variant 1, 20 µg | 20 ug |
$737.00
|
|
| TP313289 | Purified recombinant protein of Homo sapiens poly(rC) binding protein 2 (PCBP2), transcript variant 3, 20 µg | 20 ug |
$737.00
|
|
| TP325457 | Purified recombinant protein of Homo sapiens poly(rC) binding protein 2 (PCBP2), transcript variant 7, 20 µg | 20 ug |
$737.00
|
|
| TP325491 | Purified recombinant protein of Homo sapiens poly(rC) binding protein 2 (PCBP2), transcript variant 6, 20 µg | 20 ug |
$737.00
|
|
Citations
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