FAK (PTK2) (NM_005607) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC221398 |
| Predicted MW | 121.5 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_005598 |
| RefSeq Size | 4442 |
| RefSeq ORF | 3222 |
| Synonyms | FADK; FADK 1; FAK; FAK1; FRNK; p125FAK; pp125FAK; PPP1R71 |
| Locus ID | 5747 |
| UniProt ID | Q658W2 |
| Cytogenetics | 8q24.3 |
| Summary | This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jun 2017 |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Axon guidance, Chemokine signaling pathway, ErbB signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer, VEGF signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "FAK" proteins (9)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH319839 | PTK2 MS Standard C13 and N15-labeled recombinant protein (NP_722560) | 10 ug |
$3,360.00
|
|
| LC403521 | Lyophilized PTK2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC417186 | Lyophilized PTK2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC429259 | Lyophilized PTK2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY403521 | Transient overexpression lysate of PTK2 protein tyrosine kinase 2 (PTK2), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| LY417186 | Transient overexpression lysate of PTK2 protein tyrosine kinase 2 (PTK2), transcript variant 2 (as WB positive control) | 100 ug |
$665.00
|
|
| LY429259 | Transient overexpression lysate of PTK2 protein tyrosine kinase 2 (PTK2), transcript variant 2 (as WB positive control) | 100 ug |
$665.00
|
|
| TP319839 | Recombinant protein of human PTK2 protein tyrosine kinase 2 (PTK2), transcript variant 1, 20 µg | 20 ug |
$867.00
|
|
| TP321398 | Recombinant protein of human PTK2 protein tyrosine kinase 2 (PTK2), transcript variant 2, 20 µg | 20 ug |
$867.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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