GAA (NM_001079803) Human Mass Spec Standard

SKU
PH315840
GAA MS Standard C13 and N15-labeled recombinant protein (NP_001073271)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC215840
Predicted MW 105.3 kDa
Protein Sequence
Protein Sequence
>RC215840 protein sequence
Red=Cloning site Green=Tags(s)

MGVRHPPCSHRLLAVCALVSLATAALLGHILLHDFLLVPRELSGSSPVLEETHPAHQQGASRPGPRDAQA
HPGRPRAVPTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKLEN
LSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPHVHSRAPSPLYS
VEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGLAEHLSPLMLSTSWTRITLWN
RDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSV
VQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDG
FRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDF
TNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICAS
SHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPE
ILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALT
LRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLG
TWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQP
MALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQLQKVTVLGVA
TAPQQVLSNGVPVSNFTYSPDTKVLDICVSLLMGEQFLVSWC

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001073271
RefSeq Size 3597
RefSeq ORF 2856
Synonyms LYAG
Locus ID 2548
UniProt ID P10253
Cytogenetics 17q25.3
Summary This gene encodes lysosomal alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. The encoded preproprotein is proteolytically processed to generate multiple intermediate forms and the mature form of the enzyme. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2016
Protein Families Druggable Genome, Transmembrane
Protein Pathways Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism
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Other "GAA" proteins (12)
SKU Description Size Price
PH308033 GAA MS Standard C13 and N15-labeled recombinant protein (NP_001073272) 10 ug
$3,360.00
PH315796 GAA MS Standard C13 and N15-labeled recombinant protein (NP_000143) 10 ug
$3,360.00
LC400052 Lyophilized GAA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC421540 Lyophilized GAA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC421541 Lyophilized GAA HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400052 Transient overexpression lysate of glucosidase, alpha; acid (GAA), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY421540 Transient overexpression lysate of glucosidase, alpha; acid (GAA), transcript variant 2 (as WB positive control) 100 ug
$665.00
LY421541 Transient overexpression lysate of glucosidase, alpha; acid (GAA), transcript variant 3 (as WB positive control) 100 ug
$436.00
TP308033 Recombinant protein of human glucosidase, alpha; acid (GAA), transcript variant 3, 20 µg 20 ug
$737.00
TP315796 Recombinant protein of human glucosidase, alpha; acid (GAA), transcript variant 1, 20 µg 20 ug
$737.00
TP315840 Recombinant protein of human glucosidase, alpha; acid (GAA), transcript variant 2, 20 µg 20 ug
$737.00
TP701073 Purified recombinant protein of Human glucosidase, alpha, acid (GAA), with N-terminal His tag, secretory expressed in HEK293 cells, 20ug 20 ug
$900.00

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