HEPC (HAMP) (NM_021175) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC204620 |
| Predicted MW | 9.4 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_066998 |
| RefSeq Size | 430 |
| RefSeq ORF | 252 |
| Synonyms | HEPC; HFE2B; LEAP1; PLTR |
| Locus ID | 57817 |
| UniProt ID | P81172 |
| Cytogenetics | 19q13.12 |
| Summary | The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. provided by RefSeq, Oct 2014 |
| Protein Families | Secreted Protein, Transmembrane |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "HEPC" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC402850 | Lyophilized HAMP HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY402850 | Transient overexpression lysate of hepcidin antimicrobial peptide (HAMP) (as WB positive control) | 100 ug |
$436.00
|
|
| TP304620 | Recombinant protein of human hepcidin antimicrobial peptide (HAMP), 20 µg | 20 ug |
$867.00
|
|
| TP721154 | Purified recombinant protein of Human hepcidin antimicrobial peptide (HAMP) | 10 ug |
$340.00
|
|
Citations
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