Txn2 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN318507LP

Txn2 - mouse gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Donor DNA: Luciferase-Puro
• Symbol: Txn2
• Locus ID: 56551
• Components:

  KN318507G1, Txn2 gRNA vector 1 in pCas-Guide CRISPR vector

  KN318507G2, Txn2 gRNA vector 2 in pCas-Guide CRISPR vector

  KN318507LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_019913
• UniProt ID: P97493
• Synonyms: 2510006J11Rik; AI788873; Trx2
• Summary: Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity.[UniProtKB/Swiss-Prot Function]