Kmt5c Mouse Gene Knockout Kit (CRISPR)

SKU
KN317008LP
Suv420h2 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Kmt5c
Locus ID 232811
Components

KN317008G1, Kmt5c gRNA vector 1 in pCas-Guide CRISPR vector

KN317008G2, Kmt5c gRNA vector 2 in pCas-Guide CRISPR vector

KN317008LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001115018, NM_146177, NM_001358044
UniProt ID Q6Q783
Synonyms BC024816; Suv4-20h2; Suv420h2
Summary Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5C is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
GA214382 Kmt5c CRISPRa kit - CRISPR gene activation of mouse lysine methyltransferase 5C 1 kit
$1,657.00
KN317008 Kmt5c - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN317008BN Suv420h2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN317008RB Suv420h2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN517008 Suv420h2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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