Slc38a4 Mouse Gene Knockout Kit (CRISPR)

SKU KN316094BN

Slc38a4 - mouse gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Vector: mBFP-Neo
• Target Symbol: Slc38a4
• Locus ID: 69354
• Components:

  KN316094G1, Slc38a4 gRNA vector 1 in pCas-Guide CRISPR vector

  KN316094G2, Slc38a4 gRNA vector 2 in pCas-Guide CRISPR vector

  KN316094BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_027052, NM_001358058, NM_001358059, NM_001358060
• UniProt ID: Q8R1S9
• Synonyms: 1110012E16Rik; 1700012A18Rik; Ata3; mATA3; mNAT3
• Summary: Sodium-dependent amino acid transporter. Mediates electrogenic symport of neutral amino acids and sodium ions. Has a broad specificity, with a preference for Ala, followed by Ser, His, Gly, Cys, Asn, Thr, Pro, Gln and Met. May mediate sodium-independent transport of cationic amino acids, such as Arg and Lys. Amino acid uptake is pH-dependent, with lower transport activities at pH 6.5, intermediate at pH 7.0 and highest between pH 7.5 and 8.5.[UniProtKB/Swiss-Prot Function]
• Shipping: Ambient