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Satb2 Mouse Gene Knockout Kit (CRISPR)

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SKU
KN315311RB
Satb2 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

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Other products for "Satb2 or NM_139146"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Satb2
Locus ID 212712
Components

KN315311G1, Satb2 gRNA vector 1 in pCas-Guide CRISPR vector

KN315311G2, Satb2 gRNA vector 2 in pCas-Guide CRISPR vector

KN315311RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_139146, NM_001358580, NM_001358581
UniProt ID Q8VI24
Synonyms mKIAA1034
Summary Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating Bcl11b expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
GA213099 Satb2 CRISPRa kit - CRISPR gene activation of mouse special AT-rich sequence binding protein 2 1 kit
$1,657.00
KN315311 Satb2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN315311BN Satb2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN315311LP Satb2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN515311 Satb2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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