Rbm3 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN314563BN

Rbm3 - mouse gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Donor DNA: mBFP-Neo
• Symbol: Rbm3
• Locus ID: 19652
• Components:

  KN314563G1, Rbm3 gRNA vector 1 in pCas-Guide CRISPR vector

  KN314563G2, Rbm3 gRNA vector 2 in pCas-Guide CRISPR vector

  KN314563BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001166409, NM_001166410, NM_001166411, NM_001293658, NM_016809
• UniProt ID: O89086
• Synonyms: 2600016C11Rik
• Summary: Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphorylation of translation initiation factors and active polysome formation.[UniProtKB/Swiss-Prot Function]