Nfe2l2 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN310937RB

Nfe2l2 - mouse gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: Nfe2l2
• Locus ID: 18024
• Components:

  KN310937G1, Nfe2l2 gRNA vector 1 in pCas-Guide CRISPR vector

  KN310937G2, Nfe2l2 gRNA vector 2 in pCas-Guide CRISPR vector

  KN310937RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_010902, NR_132727
• UniProt ID: Q60795
• Synonyms: Nrf2
• Summary: This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. [provided by RefSeq, Sep 2015]