Mmp14 Mouse Gene Knockout Kit (CRISPR)

SKU
KN310167BN
Mmp14 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol Mmp14
Locus ID 17387
Components

KN310167G1, Mmp14 gRNA vector 1 in pCas-Guide CRISPR vector

KN310167G2, Mmp14 gRNA vector 2 in pCas-Guide CRISPR vector

KN310167BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_008608
UniProt ID P53690
Synonyms AI325305; MMP-X1; MT-MMP-1; MT1-MMP; sabe
Summary This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme. Mice lacking the encoded protein exhibit craniofacial dysmorphism, arthritis, osteopenia, dwarfism, and fibrosis of soft tissues. provided by RefSeq, Feb 2016
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Other Versions
SKU Description Size Price
GA202678 Mmp14 CRISPRa kit - CRISPR gene activation of mouse matrix metallopeptidase 14 (membrane-inserted) 1 kit
$1,657.00
KN310167 Mmp14 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN310167LP Mmp14 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN310167RB Mmp14 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN510167 Mmp14 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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