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Lgals1 Mouse Gene Knockout Kit (CRISPR)

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SKU
KN309240
Lgals1 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

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Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Vector GFP-puro
Target Symbol Lgals1
Locus ID 16852
Components

KN309240G1, Lgals1 gRNA vector 1 in pCas-Guide CRISPR vector, Target Sequence: AGAGGGTCCCGCACTCACAC

KN309240G2, Lgals1 gRNA vector 2 in pCas-Guide CRISPR vector, Target Sequence: GACAATTGGGGACTTGCTTC

KN309240D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

Homologous arm and GFP-puro sequences:

pUC vector backbone in gray; Left arm sequence in blue; GFP-puro in green; Right arm in violet

GGTGGGGCCT GTGCTTTGTG GTCCTCCTCA GTCCTCCCGC AGAAGCCCAC AGTGGGAGTC ACAGCGAGAG CCACACCCTG GCCTGCCAGG CGGCAGCCTC TTCAGAGAGC CTTGCTCTAA TTCTCTGCAG GCATCTATAC ACACATCCCC CTCCCCCACC AGCTGCGCTG GGACCTAGGG GCTTTCTCCC TGCTGGCCCC AGGCCCTATC CCGCCAACTC TTAGGTTTAA CTCATCCTTA AACTATTTTC CATTGGCTCC CCCAATCTCT GCCACAGCAC AAATCTTTTT TTAGTGGAAA GAGGGATGGA GAAGAATAAG AGGCGGCGCC AGGACCCTGA GGGAGGGGCT AGGAGGGGGG GTCTCCTCTC TGACTGGTCA CCTCTGCTCC AAAATTGACT TTATAATCCA TAGACTCCAC TTCTGGTGGC CCCCATCCTT GTCCTGACAT GCAATTGGCT GAACTCCCGG GGAGGGGCGG GACTCACCGG GTCTGATCCA GTTAAAAAGG TCGGAGCGGG CCTGGGGCCC GTCTCTCGGG TGGAGTCTTC TGACTGCTGG TGGAGCAGGT CTCAGGAATC TCTTCGCTTC AGCTTCAATC TGCCTTGGAC AGGTGTTTTC TCTGGTCCTC AGTGGCTACA TCTGTAAAAT GGGGGTGGCT GTCACTGTTC CCCCCTGAAA CCTTAAGCGT CTCTGGCTTA AGAATGTTCT GGACTTCTCG TAGTTCTGGC CGCATACCTG CCTTGCAAAG TCCAGTATTC TGCTGCTTTG CCGTTTTCTG AGAAGTGGGA GTGGGAAGGG TGTGGCCACC CGGGGAAAAG GGAGGCAGGG GGACATTTTG GCCAAGGCCA TTCCCTGTTC ACTCTTCCTC TCCACTCTAG AGTCTCCTGA CCCCTCCCCC GCTGCAGCTG TCCCCAGTCA CAGGGCCAGG GCTCAGTTGG TCACCCTCTG CTCCAGAAAA CTAAAAAAAA AAAAAAAAAA ACCCTCCCGG GCCTAAGATA GGCTCCAGGC TGGTCAGTGG AGGCGGGTCA GGGCTGGGCG GAGGAAACTG CATGCATTTG CACAGACAGG CAAGCCCTCA GGTATAGGGT TCAAATGTCA AAGAAACCCC TTGCCCAAAT GAACTCCTGT CAACTCACCC AGGTAGGTGC ACAGCAGTGC CCTGATATGT ACTGGGCTCT CTAGCGTGCT AAGTCCACAT

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_008495
UniProt ID P16045
Synonyms AA410090; Gal-1; Galbp; galectin-1; L-14.5; L14; Lect14
Summary Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
GA202442 Lgals1 CRISPRa kit - CRISPR gene activation of mouse lectin, galactose binding, soluble 1 1 kit
$1,657.00
KN309240BN Lgals1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN309240LP Lgals1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN309240RB Lgals1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN509240 Lgals1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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