Jag2 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN308538RB

Jag2 - mouse gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: Jag2
• Locus ID: 16450
• Components:

  KN308538G1, Jag2 gRNA vector 1 in pCas-Guide CRISPR vector

  KN308538G2, Jag2 gRNA vector 2 in pCas-Guide CRISPR vector

  KN308538RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_010588
• UniProt ID: Q9QYE5
• Synonyms: D12Ggc2e; mJagged2-1; Serh; sm
• Summary: Putative Notch ligand involved in the mediation of Notch signaling. Plays an essential role during limb, craniofacial and thymic development. May be involved in myogenesis and in the development of peripheral and central nervous systems.[UniProtKB/Swiss-Prot Function]