Irf5 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN308427RB

Irf5 - mouse gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: Irf5
• Locus ID: 27056
• Components:

  KN308427G1, Irf5 gRNA vector 1 in pCas-Guide CRISPR vector

  KN308427G2, Irf5 gRNA vector 2 in pCas-Guide CRISPR vector

  KN308427RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001252382, NM_001311083, NM_012057
• UniProt ID: P56477
• Synonyms: AW491843; mirf5
• Summary: Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling (By similarity).[UniProtKB/Swiss-Prot Function]