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Irak3 Mouse Gene Knockout Kit (CRISPR)

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SKU
KN308417
Irak3 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

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Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Vector GFP-puro
Target Symbol Irak3
Locus ID 73914
Components

KN308417G1, Irak3 gRNA vector 1 in pCas-Guide CRISPR vector, Target Sequence: AGGTCGAAGAGCAGCAACTG

KN308417G2, Irak3 gRNA vector 2 in pCas-Guide CRISPR vector, Target Sequence: GCAAAGCTCTCCCAGCAGTG

KN308417D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

Homologous arm and GFP-puro sequences:

pUC vector backbone in gray; Left arm sequence in blue; GFP-puro in green; Right arm in violet

CGACGGCAGG GGTTGCCTTC TGCAGCAAGG ATGAGCAGTT TGTTTGCCCA GGTTTGGCCT GTTTGTTGTG GTTTTCTTTT TATGTCCATT TCGCCCGGCG TGTACACGTT TCCTTCCGTT TAAAGTTATT TGGCAAAAAC GTGTTTCTCG GTGAGCACGC ATTTCTTTCC TGACGGGACA AAGAGAAACT TTAAAAGATG TAACACAAAC CTCTTAGATC CATCGTGGCC AGGAGGCCGC CCGTCCCAGA GCAGCAGAGG GGTGGCGGCT TTCCCGGATT CCAGCCGCTG TTCCCCGCCC TCATTTTCTT GGCTGGTCTC CTGGGTCATG TCCCAAGACG GGGACGGACA GAACGGTTCA TAACAAAGAT GACCTGGGGT GCGGCGCGCA GGGTCGCGGG ACAGCGGCTA GGAGCAAGGG CAGCCCAGGT CTCGCAGGGC GCATCCCTGG GGAGCGGCTC CCTACGTCAC GTGGGGCCCG CCCTGCGACG GCGTGTTGCA AGCTCCGGGC AGCCGTCGTG GAGCTGAATT TCCGCGGTTG TGAAAGGCGG TGACAGCGGC GACCTCCCTG CTTCTCTGCG TGGGGTCCCG GGACTCCGCG TGCGATGGCC CGCTCGGCTG GCGGGGCCTG GGTGAGTGCG ACTCAGACCT GCCGGTCCTC CCCCGCGAGG GACTCAGCAA ACCCGGGGAC CTGCCACTCA CTCTCCTTCC CTCTCTGACA GTGGGGTACT GCTGTATCAA GTTAGGGGAT TGGGTATGTC AGATGTCAAG AAAGCATCCC GTGCTGGGAA GAGATTCTCG CTTCACTCGG TTTGCAGTGT GCGCAGCAGT ATGCAAATAT TACCGTATGC AGGGCATGGC TACTGGCTCT ACAACCCCTA CATCAGATTT TTTTAATATT ATAACTTCTT TTTTGAGATG CCGCTCAGTT GCTAGAGTGC TTACCTATAG ATGTATGAAG CTGCATGTTC GATTCCCTAG CTTGGAATAA AACAGACAGT GGTAGTGCCA GTCATTGAGA GGTAGAAGTA GGCAGGACAG ATGCTCAAGA GCATCCTCTC CTTGTAGAGA GTTCCTAGCT GGCTTGGGAA ACATGAGACG CCATCTCAAA AACAAAAAGC AAACTTACTT TCTTTTCTTT CCTTTCTTTC TTTCTTTCTT TCTTTCTTTC TTTCTTCCTT CCTTCCTTCC TTCCTTCCTT

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_028679, NR_152856, NM_001359184
UniProt ID Q8K4B2
Synonyms 4833428C18Rik; AI563835; IRAK-M
Summary Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
GA209645 Irak3 CRISPRa kit - CRISPR gene activation of mouse interleukin-1 receptor-associated kinase 3 1 kit
$1,657.00
KN308417BN Irak3 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN308417LP Irak3 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN308417RB Irak3 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN508417 Irak3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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